Release Date: May 2019
CC: PC, MK, PBL, SBP
Patrick A. Erdman, DO
Assistant Attending Physician and Assistant Clinical Member, Memorial Sloan Kettering Cancer Center, New York, NY
After completing this course, participants will be able to:
Describe common specimen interferences seen in the clinical laboratory.
Differentiate the different types of pre-analytic factors (i.e., disease-specific, patient-specific, iatrogenic, etc.).
Explain how instrument measurement parameters and rules can provide clues to a possible interference.
Who should attend? Practicing Pathologists, Residents, Doctoral Scientists, Laboratory Managers, Bench Supervisors, Bench Technologists & Technicians, Students
This webcast will provide an overview of common and uncommon interfaces seen in the clinical laboratory. The format will be through a case-based approach, highlighting several examples of specimen interferences. The course will highlight the different types of pre-analytical factors that can cause a specimen interference and will discuss how some instrument parameters can be used as an indicator or clue of a specimen interference. Beyond specific case-based examples, there will also be a didactic section on typical specimen interferences such as lipemia, hemolysis, etc. and steps that have been taken to reduce the incidence. The order of blood draw will be highlighted as a cause of pre-analytic interferences, based on a recent opinion paper from the European Federation of Clinical Chemistry and Laboratory Medicine Working Group. Finally, there will be a discussion on the incidence of specimen interferences in the clinical laboratory.