Order # 5725 | ISBN: 9780891895725 Authors
Emina Torlakovic, MD, PhD
Kikkeri Naresh, MBBS, CCP, MD, FRCPath
and Richard D. Brunning, MD Description
Despite advances in flow cytometry and molecular methods, immunohistochemistry (IHC) remains an important, useful, and cost-effective component of the diagnostic evaluation of most bone marrow biopsies. In fact, the use of IHC promises to grow as the menu of primary antibodies that can be applied to bone marrow biopsy grows at an exponential rate.
Yet, to date, there has been no single resource that addresses the utility of individual IHC markers, their selection, and their appropriate application and interpretation in specific disease processes involving the bone marrow. By providing a comprehensive overview of the use of IHC markers in bone marrow biopsies, Bone Marrow IHC fills this critical gap in the literature.
Bone Marrow IHC provides a rich collection of color illustrations that demonstrate the diagnostic features of antibodies applicable to bone marrow tissue. Each of the antibodies illustrated in the volume includes a systematic description that details an expected reaction profile in both normal bone marrow cells and neoplastic cells, as well as authoritative advice about avoiding potential diagnostic pitfalls and technical problems related to the antibodies and tissue processing.