Reflexing Suspicious ß-Region Findings on Capillary Serum Protein Electrophoresis to Immunofixation or Immunosubtraction for Detecting Monoclonal Proteins

Online journal article in Hematopathology that offers 1.0 continuing education (CME) credit that can be used to fulfill CC Part II requirements.

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Intended Audience: Pathologists, Residents, Clinical Scientists, Pathologist Assistants

Upon completion of this activity, you will be able to:

Describe the challenges of detecting monoclonal immunoglobulin proteins (M-proteins) that migrate in the beta region during serum electrophoresis.

Intended Audience: Pathologists, Residents, Clinical Scientists, Pathologist Assistants

Upon completion of this activity, you will be able to:

Describe the challenges of detecting monoclonal immunoglobulin proteins (M-proteins) that migrate in the beta region during serum electrophoresis.
Discuss the likelihood of M-protein isotypes being found in the beta region
Use measurement of the beta1 and beta2 regions as a basis to perform immunofixation
Detect beta region M-proteins by reflexing even small suspicious beta region bands for immunofixation

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