Activity Overview
This activity is designed to help pathologists and laboratory professionals learn how PD-L1 testing, and interpretation is performed using the combined positive score (CPS). Panelists will review how CPS is used to determine PD-L1 positivity. They will also describe some of the challenges associated with scoring certain types of cancers using CPS. Panelists will list some practical ways to ensure optimal PD-L1 testing and scoring using CPS.
Target Audience
This activity has been designed to meet the educational needs of pathologists and laboratory professionals diagnosing cancer.
Activity Agenda
· Introductions
· Review the definition of combined positive score (CPS)
· Panel discussion: what makes CPS so challenging
· Recommended steps to improve PD-L1 testing and scoring
· Summary of key takeaways
Learning Objectives
Upon completion of this activity, you will be able to:
· Describe how PD-L1 expression is determined using combined positive score (CPS).
· Outline some of the challenges pathologists face when using combined positive score (CPS).
· Discuss ways to achieve accurate assessment of PD-L1 protein expression when using combined positive score (CPS).
Faculty
|
Wei Zhang, MD, PhD |
Assistant Professor, Pathology and Laboratory Medicine
Medical Director of Molecular Pathology in Solid Tumor, Pathology and Laboratory Medicine
University of Kansas |
|
Stuti Shroff, MD, PhD |
Assistant Professor of Pathology, Harvard Medical School
Assistant Pathologist, Anatomic and Molecular Pathology, Massachusetts General Hospital |
|
Lamees Saeed, MD |
Breast and Molecular Pathology Fellow at Moffitt Cancer Center |
|
Joseph Kim, MD |
President of Q Synthesis LLC |
Faculty Disclosures
Wei Zhang, Stuti Shroff, Lamees Saeed, and Joseph Kim have no relevant financial relationships to disclose.
Accreditation Statement
The American Society for Clinical Pathology (ASCP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education (CME) for physicians.
Credit Designation Statement
The American Society for Clinical Pathology (ASCP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education (CME) for physicians.
The ASCP designates this activity for a maximum of 0.5 AMA PRA Category 1 Credit(s)â„¢. Physicians should claim only credit commensurate with the extent of their participation in the activity.
ASCP designates this activity for a maximum of 0.5 CMLE credit. This activity meets CMP and state re-licensure requirements for laboratory personnel.
For questions regarding CME credit, please contact ASCP Customer Service at 1-800-267-2727, during normal business hours: Monday through Friday, 8 a.m. to 6 p.m. Eastern Time.
Method of Participation
To complete the activity and receive credit, the participant must complete the online activity. CME certificates will be provided online.
Commercial Support
This activity is funded by an independent educational grant from Merck.