Is the automated Elecsys tacrolimus assay on the Roche cobas e 602 analyzer an acceptable replacement for a liquid chromatography–tandem mass spectrometry–based assay?

Online journal article in Clinical Chemistry that offers 1.0 continuing education (CME) credit that can be used to fulfill CC Part II requirements.

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Intended Audience: Pathologists, Residents, Clinical Scientists, Pathologist Assistants

Upon completion of this activity, you will be able to:

describe the clinical use of tacrolimus and the physiologic factors that can affect its therapeutic range.
list laboratory challenges in determining the...

Intended Audience: Pathologists, Residents, Clinical Scientists, Pathologist Assistants

Upon completion of this activity, you will be able to:

describe the clinical use of tacrolimus and the physiologic factors that can affect its therapeutic range.
list laboratory challenges in determining the therapeutic range of tacrolimus.
compare the results of the Elecsys Tacrolimus assay on the Roches cobas e603 to those obtained with a liquid chromatography tandem mass spectrometry (LC-MS/MS)-based assay.

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