This case-based activity is designed to help pathologists and laboratory professionals increase their knowledge, skills, and competence in applying practice-changing updates regarding HER2-low and HER2-ultralow advanced breast cancer. Through three case-based microlearning activities learners will answer questions designed to help them carefully consider the nuances of HER2-low and HER2-ultralow breast cancer diagnosis. This is the third of the three activities and focuses on reproducibility of testing and clinical significance of HER2-low and HER2-ultralow.
Course Topics Include:
- Interobserver variability in HER2 IHC scoring
- Clinical significance of HER2-low and HER2-ultralow
Target Audience
This activity has been designed to meet the educational needs of pathologists and laboratory professionals.
Learning Objectives
Upon completion of this activity, you will be able to:
- Discuss the interobserver variability in HER2 IHC scoring and its impact on treatment decisions
- Describe the clinical significance of low and ultra-low HER2 expression in breast cancer
- Explain the implications of HER2 reassessment in recurrent disease
Faculty
Aysegul Sahin
Professor, Department of Pathology, Division of Pathology/Lab Medicine
The University of Texas MD Anderson Cancer Center, Houston, TX
Faculty Disclosures
Dr. Sahin has no relevant financial relationships to disclose.
Accreditation Statement
The American Society for Clinical Pathology (ASCP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education (CME) for physicians.
Credit Designation Statement
The ASCP designates this activity for a maximum of .25 AMA PRA Category 1 Credit(s)â„¢. Physicians should claim only credit commensurate with the extent of their participation in the activity.
ASCP designates this activity for a maximum of .25 CMLE credit. This activity meets CMP and state re-licensure requirements for laboratory personnel.
For questions regarding CME credit, please contact ASCP Customer Service at 1-800-267-2727, option 2, in the US & Canada or internationally at access code + 3-1-312-541-4890. Monday-Friday, 8am-5pm CT.
Method of Participation
To complete the activity and receive credit, the participant complete the program. CME certificates will be provided online.
Commercial Support
This activity is supported by independent educational grants from AstraZeneca Pharmaceuticals and Daiichi Sankyo, Inc.