Case Reports Surgical Pathology 2017 Exercise 1: Solar Keratosis of the Nail Bed With Progression to Squamous Cell Carcinoma (CSSP1701)

Intended Audience: Pathologists, Residents, Clinical Scientists, Laboratory Technologist/Scientist (Includes all sub-specialty areas), Students, Pathologist Assistants,  Laboratory Directors and Educators

Upon completion of this activity, you will be able to:

• describe the differences in the histologic characteristics of cells commonly found in the skin versus those found in the nail bed;
• identify the most common risk factor and molecular mutation related to solar keratosis;
• describe the relationship of solar keratosis to excessive exposure to sunlight, even under nails, and how this precancerous lesion may lead to squamous cell carcinoma; and
• distinguish the clinical findings of subungual squamous cell carcinoma from other benign entities.