Case Reports Hematopathology 2018 Exercise 6: Blastic Plasmacytoid Dendritic Cell Neoplasm in in A child (CSHP1806)

Ji Yuan, MD, PhD
Assistant Professor

Kai Fu, MD, PhD
Professor

Department of Pathology and Microbiology
University of Nebraska Medical Center
Omaha, Nebraska

Primary Audience: Pathologists and Clinical Scientists

Secondary Audience: Residents, Laboratory Technologist/Scientist (Includes all sub-specialty areas), Students, Pathologist Assistants,  Laboratory Directors and Educators

Upon completion of this activity, you will be able to:

• recognize the clinical presentation of blastic plasmacytoid dendritic cell neoplasm (BPDCN);
• delineate the morphologic and immunophenotypic features of BPDCN;
• recognize the characteristic profiles of BPDCN by flow cytometry;
• differentiate BPDCN from other myeloid/monocytic neoplasms and T/natural killer (NK)-cell leukemia/lymphoma; and
• differentiate BPDCN from benign counterparts associated with myeloid disorders.