Release Date: Apr 2018
CC: PC, MK, PBL, ICS, PR, SBP
Teri A. Longacre, MD
Professor of Pathology, Stanford University School of Medicine, Stanford, CA
Squamous lesions of the lower female genital tract continue to pose diagnostic problems for the surgical pathologist. This webcast focuses on unusual and/or difficult variants of squamous intraepithelial neoplasia including differentiated vulvar lesions and the diagnosis (and measurement) of superficial invasion. Using a case-based format, criteria for distinguishing clinical and pathological mimics (vulvar dystrophy, Paget’s disease, dermatoses, immature metaplasia, etc.) are presented. The indications and appropriate utilization of biomarkers (p16, Ki-67, p53) are also emphasized. Throughout the webcast, the approach to interpretation of small or suboptimal samples and other potential pitfalls is provided.
After attending this session, participants will be able to:
- Diagnose and report squamous intraepithelial lesions (SIL) and distinguish them from common and not-so-common mimics.
- Identify differentiated vulvar intraepithelial neoplasia (dVIN) based on strict diagnostic criteria.
- Utilize biomarkers in the differential diagnosis of lower genital tract squamous lesions.
Who should attend? Practicing Pathologists, Residents, Gynecologists