Release Date: Jun 2018
CC: PC, MK, PBL, SBP
Lynsi Rahorst, MHPE, MT(ASCP)SBBCM
Education Coordinator and IRL Technologist, Community Blood Center of Kansas City, Kansas City, MO
While the HLA (Human Leukocyte Antigen) system and its associated antigens and antibodies are important in solid organ and hematopoietic progenitor cell transplantation, blood bankers should understand the role of HLA antigens and antibodies in transfusion. While this webcast will not dive deeply into the ever-increasing complexities of the HLA system, it will address information that blood bankers should know as they strive to provide safe and effective components for transfusion. Following a basic overview of the HLA system, this webcast will discuss HLA antibody interference in red blood cell antibody identification, the role of the HLA system in platelet refractoriness, and transfusion reactions associated with HLA antigens and antibodies.
After attending this session, participants will be able to:
- Discuss how HLA antibodies may interfere with red cell antibody identification and how they are circumvented, and transfusion recommendations for patients with HLA antibodies.
- Explain how HLA antibodies may affect platelet transfusion, and list options for transfusion in cases of platelet refractoriness.
- List and describe transfusion reactions associated with the HLA system.
Who should attend? Residents, Laboratory Managers, Bench Supervisors, Bench Technologists and Technicians, Students