Case Reports Forensic Pathology 2023 Exercise 5: Nephrocalcinosis and End-Stage Renal Disease Resulting from Amyloidosis Secondary to Injection Drug Use

Authors

Michael Brown, DO

Department Of Laboratory Medicine and Pathology

University Of Washington School of Medicine

Nicole Yarid, MD

King County Medical Examiner's Office

Seattle, Washington

Primary Audience: Pathologists and Clinical Scientists
Secondary Audience: Residents, Laboratory Technologist/Scientist (Includes all sub-specialty areas), Students, Pathologist Assistants, Laboratory Directors and Educators

Upon completion of this activity, you will be able to:

·         discuss the most common causes of secondary amyloidosis;

·         describe the histologic findings diagnostic of renal amyloidosis and special features associated with rapid progression to end-stage renal disease;

·         distinguish between ancillary testing modalities used to diagnose and subtype amyloidosis;

·         identify the top differential diagnoses associated with renal amyloidosis; and

·         recognize the clinical features of nephrocalcinosis.