NGS Testing for DNA Repair Gene Mutations in Prostate Cancer

This activity is designed to engage pathologists, laboratory professionals, and other members of the multidisciplinary cancer care team in improving their knowledge, skills, and competence related to NGS testing and reporting in prostate cancer.

·       Course topics include: 

·       Advantages of NGS testing and reporting in prostate cancer

·       Strategies to effectively test for homologous recombination repair mutations in prostate cancer

·       Considerations for NGS adoption, including:

o   Specimen quality/adequacy and testing

o   Potential pitfalls

o   Available diagnostic tests for HRR mutations

o   NGS reporting considerations

·       Importance of partnering with the multidisciplinary cancer care team to utilize NGS testing for patients with prostate cancer

 Target Audience 

This activity has been designed to meet the educational needs of pathologists and laboratory professionals. 

 Learning Objectives 

Upon completion of this activity, you will be able to: 

·       Implement strategies to effectively test for HRR mutations based on expert guidance on timing and testing methodologies from blood or tissue

·       Apply multidisciplinary care team communication and workflow strategies for pathological reporting of HRR mutations, considering the implications of misdiagnosis and suboptimal treatment regimens.

Faculty

Colin C. Pritchard, M.D., Ph.D.
Associate Professor of Laboratory Medicine, University of Washington (UW)
Director of the Genetics and Solid Tumors Laboratory at UW Medical Center
Seattle, WA

Faculty disclosures

Colin C. Pritchard, M.D., Ph.D. has no relevant financial relationships to disclose.

Credit Designation Statement