Authors
Robert D. Nerenz, PhD
Yasel F. Alvarez, PhD
Department of Pathology and Laboratory Medicine
Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire
Primary Audience: Pathologists and Clinical Scientists
Secondary Audience: Residents, Laboratory Technologist/Scientist (Includes all sub-specialty areas), Students, Pathologist Assistants, Laboratory Directors and Educators
Upon completion of this activity, you will be able to:
· discuss the definition and diagnostic criteria for hypertensive disorders in pregnancy (preeclampsia) as outlined by the American College of Obstetricians and Gynecologists (ACOG);
· recognize the signs and symptoms, risk factors, and clinical laboratory blood tests relevant to the diagnosis of preeclampsia;
· identify novel screening methods based on angiogenic biomarkers such as soluble FMS-like tyrosine kinase (sFlt-1), soluble endoglin (sENG), and proangiogenic placental growth factor (PlGF) and their potential to identify patients at risk for developing preeclampsia; and
· evaluate ACOG-recommended prevention strategies, therapeutic approaches, and management of preeclampsia.