Case Reports Forensic Pathology 2022 Exercise 5: Traumatic Splenic Rupture Complicating B-Cell Acute Lymphoblastic Leukemia

Authors

Stefanie Grewe, MD

Jasmine Richards, MBS

Medical Student

Susan Erin Presnell, MD

Angelina Phillips, MD

Medical University of South Carolina

Charleston, South Carolina

Primary Audience: Pathologists and Clinical Scientists
Secondary Audience: Residents, Laboratory Technologist/Scientist (Includes all sub-specialty areas), Students, Pathologist Assistants,  Laboratory Directors and Educators

Upon completion of this activity, you will be able to:

·         discuss the differential diagnosis of splenomegaly to guide postmortem ancillary testing;

·         describe the risk factors identified in cases of splenic rupture;

·         recognize the importance of collecting antemortem hospital blood samples to evaluate the causes of splenomegaly and diagnose hematopoietic disorders; and

·         explain to family members how unexpected autopsy findings of malignancy may be a factor in the cause of death.