Case Reports Cytopathology 2023 Exercise 6: Submucosal Duodenal Mass in a Patient with a History of Granulosa Cell Tumor: Cytologic/Histologic Correlation and Pitfalls

Authors

Afreen Karimkhan, MD

Department of Pathology

NYU Langone Health

New York, New York

Tamar C. Brandler, MD MS

Department of Pathology

Division of Cytopathology

Rutgers Robert Wood Johnson Medical School

New Brunswick, New Jersey

Primary Audience: Pathologists and Clinical Scientists
Secondary Audience: Residents, Laboratory Technologist/Scientist (Includes all sub-specialty areas), Students, Pathologist Assistants, Laboratory Directors and Educators

Upon completion of this activity, you will be able to:

·         recognize cytologic features of granulosa cell tumors (GCTs);

·         distinguish characteristics of metastatic GCTs from other submucosal duodenal lesions;

·         differentiate features of GCT from other entities with similar immunohistochemical staining properties; and

·         identify key ancillary studies including immunohistochemical and molecular studies that support the diagnosis of GCT.