Author
Jane Nguyen, MD, PhD
Department of Pathology
Cleveland Clinic
Cleveland, Ohio
Primary Audience: Pathologists and Clinical Scientists
Secondary Audience: Residents, Laboratory Technologist/Scientist (Includes all sub-specialty areas), Students, Pathologist Assistants, Laboratory Directors and Educators
Upon completion of this activity, you will be able to:
· identify histologic correlates of glomerular disease in the setting of sudden-onset nephrotic syndrome;
· discuss the differential diagnosis of diffuse podocytopathy in the clinical workup for nephrotic syndrome;
· establish the diagnosis of minimal change disease utilizing light microscopy findings, immunofluorescence, and electron microscopy;
· explain the clinical manifestations, treatment, and prognosis of minimal change disease; and
· discuss new advances in a novel autoimmune etiology for podocytopathy.