Case Reports Renal Pathology 2022 Exercise 1: Light Chain Cast Nephropathy, Intratubular Amyloid Variant

Author

Dominick Santoriello, MD

Columbia University Irving Medical Center

New York, New York

Primary Audience: Pathologists and Clinical Scientists
Secondary Audience: Residents, Laboratory Technologist/Scientist (Includes all sub-specialty areas), Students, Pathologist Assistants, Laboratory Directors and Educators

Upon completion of this activity, you will be able to:

·       describe the typical clinical presentation of light chain cast nephropathy (LCCN);

·       describe the proposed mechanism of cast formation in LCCN;

·       describe the classic pathologic features of LCCN;

·       describe potential mimickers of LCCN; and

·       describe the pathologic features and clinical relevance of the intratubular amyloid variant of LCCN.