Case Reports Renal Pathology 2022 Exercise 2: Syphilis-Related Acute Postinfectious Glomerulonephritis

Authors

Simon Walker, MD

Jean Hou, MD

Department of Pathology

Cedars Sinai Medical Center

Los Angeles, California

Primary Audience: Pathologists and Clinical Scientists
Secondary Audience: Residents, Laboratory Technologist/Scientist (Includes all sub-specialty areas), Students, Pathologist Assistants, Laboratory Directors and Educators

Upon completion of this activity, you will be able to:

·       explain the pertinent pathologic findings of acute postinfectious glomerulonephritis (APIGN);

·       discuss the different pathologic and clinical subtypes of APIGN;

·       compare the clinical presentations and clinical courses of pediatric and adult PIGN;

·       evaluate the pertinent pathologic and clinical features that help differentiate APIGN from other glomerular diseases in the differential diagnosis;

·       develop a differential diagnosis for the different glomerular diseases that are associated with syphilis infection; and

·       develop an assessment plan for pertinent laboratory assays that help in diagnosis of APIGN.