Case Reports Clinical Chemistry 2023 Exercise 3: Recent Advances in Cystic Fibrosis Diagnosis and Management

Authors

Erving T. Laryea, PhD

Joesph R. Wiencek, PhD, DABCC, FAACC

Department of Pathology, Microbiology, and Immunology

Vanderbilt University Medical Center

Nashville, Tennessee            

Primary Audience: Pathologists and Clinical Scientists
Secondary Audience: Residents, Laboratory Technologist/Scientist (Includes all sub-specialty areas), Students, Pathologist Assistants,  Laboratory Directors and Educators

Upon completion of this activity, you will be able to:

·         identify the CFTR genetic mutation associated with each class of cystic fibrosis;

·         recognize the body systems affected by cystic fibrosis and the symptoms associated with them;

·         describe the role of laboratory tests in the detection, diagnosis, and confirmation of cystic fibrosis;

·         discuss the algorithms followed to diagnose cystic fibrosis; and

·         explain how the newer therapy options help in the management of cystic fibrosis.