Case Reports Surgical Pathology 2023 Exercise 4: Stromal Tumor of Uncertain Malignant Potential in the Prostate: Case Report and Review of the Diagnostic Considerations and Differential Diagnosis

Authors

Anthony Jake Emanuel, MD

Nicholas Anthony Lariccia, MD

Andrew D. Hardie, MD

Laura Simmons Spruill, MD, PhD

Medical University of South Carolina

Charleston, South Carolina

Primary Audience: Pathologists and Clinical Scientists
Secondary Audience: Residents, Laboratory Technologist/Scientist (Includes all sub-specialty areas), Students, Pathologist Assistants, Laboratory Directors and Educators

Upon completion of this activity, you will be able to:

·         identify cases for which prostatic stromal tumor of uncertain malignant potential (STUMP) should be considered;

·         discuss the important differential diagnoses for hypercellular prostate stroma, including benign prostatic hyperplasia and STUMP;

·         incorporate clinical, radiographic, and histologic findings to support a diagnosis of STUMP;

·         explain the clinical importance of STUMP regarding treatment and potential progression;

·         differentiate STUMP from prostatic stromal sarcoma; and

·         evaluate prostatic stromal lesions for prostatic stromal sarcoma and the other entities in the differential.