Case Reports Transfusion Medicine 2023 Exercise 1: Something to Taco About: Transfusion-Associated Circulatory Overload

Authors

Robert Frick, MD

Department of Pathology and Immunology

Washington University School of Medicine

St Louis, Missouri

Nicholas Gau, MD

Department of Pathology

Sanford Health

Fargo, North Dakota

Primary Audience: Pathologists and Clinical Scientists
Secondary Audience: Residents, Laboratory Technologist/Scientist (Includes all sub-specialty areas), Students, Pathologist Assistants,  Laboratory Directors and Educators

Upon completion of this activity, you will be able to:

·         recognize possible transfusion-associated circulatory overload (TACO) based on vital sign changes and symptoms during or shortly after transfusion;

·         correlate the proposed mechanism(s) underlying TACO with known patient risk factors;

·         compare and contrast TACO with transfusion-related acute lung injury (TRALI); and

·         evaluate patient- and product-centered prevention strategies for TRALI.