Case Reports Transfusion Medicine 2023 Exercise 4: Blood Bank Testing and its Challenges

Authors

Gian Piero Carames, MD

Department of Pathology

Heersink School of Medicine

Nirupama Singh, MD, PhD

Department of Medicine

The University of Alabama at Birmingham

Birmingham, Alabama

Primary Audience: Pathologists and Clinical Scientists
Secondary Audience: Residents, Laboratory Technologist/Scientist (Includes all sub-specialty areas), Students, Pathologist Assistants,  Laboratory Directors and Educators

Upon completion of this activity, you will be able to:

·         discuss basic pretransfusion testing;

·         discuss additional workup performed for panreactive antibodies;

·         discuss high-frequency red blood cell antigens and describe characteristics of high-titer low-avidity antibodies; and

·         describe techniques to avoid interference to newer immunotherapy (anti-CD47 and anti-CD38).