LabQ Clinical 2025 Exercise 18: Transfusion Medicine: Exchange Transfusion as an Emergency Treatment for Hyperbilirubinemia for Hemolytic Disease of the Newborn

Author(s)

Hayat Safi, MLS (ASCP)CM, SBBCM

Laurie Gillard, MS, MLS(ASCP)CM, SBBCM

Mark Pool, MD

Rush University

Chicago, Illinois

Primary Audience: Pathologists and Clinical Scientists
Secondary Audience: Residents, Laboratory Technologist/Scientist (Includes all sub-specialty areas), Students, Pathologist Assistants,  Laboratory Directors and Educators

Upon completion of this activity, you will be able to:

·       define Immune Hyperbilirubinemia, Hemolytic Disease of the Fetus and Newborn (HDFN), exchange transfusion, and reconstituted whole blood;

·       identify the clinical indications for performing an exchange transfusion in neonates;

·       recommend blood products for an exchange transfusion; and

·       identify potential complications associated with exchange transfusion, such as infection, electrolyte imbalances, and adverse reactions.