LabQ Clinical 2025 Exercise 7: Hematology: Hepatosplenic T-Cell Lymphoma

Author(s)

Wei J Wang, MD

Jie Xu, MD PhD

MD Anderson Cancer Center

University of Texas

Houston, Texas

Primary Audience: Pathologists and Clinical Scientists
Secondary Audience: Residents, Laboratory Technologist/Scientist (Includes all sub-specialty areas), Students, Pathologist Assistants,  Laboratory Directors and Educators

Upon completion of this activity, you will be able to:

·       describe the clinical presentation of a patient with hepatosplenic T-cell lymphoma (HSTCL);

·       describe the morphologic features of HSTCL cells seen in peripheral blood and bone marrow smears;

·       discuss the immunophenotype of HSTCL;

·       discuss the differential diagnosis of HSTCL; and

·       discuss the prognosis of patients with HSTCL.