Revision of interpretation criteria to define microsatellite instability in mismatch repair deficient neoplasms with subtle electropherogram changes

Online journal article in Molecular Pathology that offers 1.0 continuing education (CME) credit that can be used to fulfill CC Part II requirements.

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Intended Audience: Pathologists, Residents, Clinical Scientists, Pathologist Assistants

Upon completion of this activity, you will be able to:

Summarize the rationale for using mononucleotide microsatellite loci rather than nucleotide microsatellite loci when performing assays to detect...

Intended Audience: Pathologists, Residents, Clinical Scientists, Pathologist Assistants

Upon completion of this activity, you will be able to:

Summarize the rationale for using mononucleotide microsatellite loci rather than nucleotide microsatellite loci when performing assays to detect microsatellite instability (MSI).

Outline the recommendations for MSI testing published in the guideline of the College of American Pathologists that was endorsed by the American Society of Clinical Oncology.

Describe the efficacy and the limitations of the revised criteria of MSI as defined by the authors in this paper.

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