Case Reports Clinical Chemistry 2024 Exercise 1: Assessment and Management of Hyperviscosity Syndrome in the Chemistry Laboratory

Author

Ria C. Fyffe-Freil, PhD

Department of Pathology, Microbiology and Immunology

University of Nebraska Medical Center

Omaha, Nebraska

Primary Audience: Pathologists and Clinical Scientists
Secondary Audience: Residents, Laboratory Technologist/Scientist (Includes all sub-specialty areas), Students, Pathologist Assistants,  Laboratory Directors and Educators

Upon completion of this activity, you will be able to:

·         recognize analytic signs of serum hyperviscosity from common laboratory test results;

·         explain the basic pathophysiology of disease that can cause the accumulation of proteins in the serum;

·         describe the critical importance of early recognition of hyperviscosity syndrome;

·         construct a strategic plan to identify and troubleshoot hyperviscous samples; and

·         explain the methodology for measuring serum viscosity in the clinical laboratory.