Case Reports Hematopathology 2024 Exercise 1: Thymoma-Associated Good Syndrome Diagnosed by Morphologic and Immunophenotypic Abnormalities in Excised Lymph Nodes

Authors

Leah J. Gruen, BA

Medical Student

Erik A. Ranheim, MD, PhD

Department of Pathology and Laboratory Medicine

University of Wisconsin-Madison School of Medicine and Public Health

Madison, Wisconsin

Primary Audience: Pathologists and Clinical Scientists
Secondary Audience: Residents, Laboratory Technologist/Scientist (Includes all sub-specialty areas), Students, Pathologist Assistants,  Laboratory Directors and Educators

Upon completion of this activity, you will be able to:

·         synthesize histologic findings in lymph nodes with clinical laboratory data to aid in differential diagnoses, including Good syndrome;

·         investigate nonneoplastic causes of lymph node abnormalities found on staging specimens;

·         utilize medical record review in a patient with thymoma biopsy or excision to detect and report possible autoimmune-associated disorders; and

·         explain the mechanism of increased infection susceptibility in Good syndrome and the basis for typical therapies.