Author
Mariko Yabe, MD, PhD
Department of Pathology and Laboratory Medicine
Memorial Sloan Kettering Cancer Center
New York, New York
Primary Audience: Pathologists and Clinical Scientists
Secondary Audience: Residents, Laboratory Technologist/Scientist (Includes all sub-specialty areas), Students, Pathologist Assistants, Laboratory Directors and Educators
Upon completion of this activity, you will be able to:
· Summarize the clinicopathologic features of three major types of histiocytosis; Erdheim-Chester disease (ECD), Langerhans cell histiocytosis (LCH) and Rosai-Dorfman disease (RDD);
· Understand the genetic features of histiocytosis;
· Define the entity “mixed histiocytosis;” and
· Utilize appropriate immunohistochemical and molecular genetic ancillary tests to accurately diagnose histiocytosis.