Case Reports Cytopathology 2022 Exercise 5: Malignant Gastrointestinal Neuroectodermal Tumor in Abdominal Fluid

Author

Keenan Odell Hogan, MD

Department of Pathology and Laboratory Medicine

University of Kansas Medical Center

Kansas City, Kansas

Primary Audience: Pathologists and Clinical Scientists
Secondary Audience: Residents, Laboratory Technologist/Scientist (Includes all sub-specialty areas), Students, Pathologist Assistants, Laboratory Directors and Educators

Upon completion of this activity, you will be able to:

·       recognize the cytomorphologic features of gastrointestinal neuroectodermal tumor (GNET) in peritoneal fluid cytology specimens using air-dried and alcohol-fixed preparations;

·       select optimal cytology specimen triage for the diagnostic workup of GNET;

·       choose an appropriate panel of ancillary studies to confirm the diagnosis of GNET;

·       distinguish pathologic entities in the differential diagnosis of GNET by their primary cytomorphologic, immunohistochemical, and molecular characteristics; and

·       discuss the clinical prognosis and management of GNET.