Case Reports Cytopathology 2025 Exercise 4: Solitary Fibrous Tumor Presenting as a Posterior Mediastinal Mass, a Challenging Diagnosis by Cytopathology

Authors

John Colavito, MD

Rong Xia, MD, PhD

Jing Wang, MD

New York University Grossman School of Medicine

Nyu Langone Health

New York, New York

Primary Audience: Pathologists and Clinical Scientists
Secondary Audience: Residents, Laboratory Technologist/Scientist (Includes all sub-specialty areas), Students, Pathologist Assistants,  Laboratory Directors and Educators

Upon completion of this activity, you will be able to:

·       describe the cytomorphologic features of solitary fibrous tumor;

·       develop a differential diagnosis for an intrathoracic spindle cell neoplasm;

·       explore the role of ancillary immunohistochemical and molecular techniques available to distinguish solitary fibrous tumor from diagnostic mimickers; and

·       gain a practical understanding of classification and grading of solitary fibrous tumors through the perspective of a practicing cytopathologist.