Case Reports Surgical Pathology 2022 Exercise 1: IgG4-Related Disease

Authors

Asha Sigei, MD

Corynne Caballero, MD

Jacob Snyder, DO

Kathryn G. Lindsey, MD

Department of Pathology & Laboratory Medicine

Medical University of South Carolina

Charleston, South Carolina

Primary Audience: Pathologists and Clinical Scientists
Secondary Audience: Residents, Laboratory Technologist/Scientist (Includes all sub-specialty areas), Students, Pathologist Assistants, Laboratory Directors and Educators

Upon completion of this activity, you will be able to:

·       explain some of the history of IgG4-related disease and the comparative research findings that unified the diagnosis;

·       describe the characteristic histopathologic features of IgG4-related disease and IgG4-related lymphadenopathy;

·       review the Boston Criteria used in assessing IgG4-related disease;

·       recognize common presentations of IgG4-related disease and the histologic features that support the diagnosis; and

·       differentiate reactive and neoplastic lymphadenopathy from IgG4-related lymphadenopathy.